Asthma: a chronic disease still poorly managed in France

Press

On the occasion of World Asthma Day, the experts of the CRISALIS network (F-CRIN) are sounding the alarm. major advances in recent years, this chronic disease is still largely underestimated and inadequately with almost 900 deaths per year. The challenge today is to provide better training and support for the professionals involved, to improve prevention and ensure more consistent care across the country. throughout the country.

A chronic disease... still too often trivialized

Asthma affects between 6% and 8% of the French population and is responsible for 60,000 hospitalizations every year. This pathology manifests itself as inflammation of the bronchial tubes, leading to episodes of respiratory discomfort, wheezing and coughing, varying in intensity from patient to patient. Contrary to popular belief, this is not a one-off illness. It is a chronic inflammatory disease that evolves throughout life, with phases of lull that can give the illusion of a cure, without it being real. In reality, this chronic dimension is still poorly integrated. Asthma is too often considered as a simple antecedent, and not as a pathology requiring regular, structured follow-up; a trivialization contributing to insufficient and sometimes inappropriate management.

Practices still far from recommendations

International recommendations, notably those of the Global Initiative for Asthma (GINA), have profoundly changed the way the disease is managed. They emphasize a major change: treatments based solely on short-acting bronchodilators are no longer suitable. Now, the use of inhaled corticosteroids is recommended, including in patients with infrequent symptoms. But these recommendations are still unevenly applied, particularly in primary care medicine, due to a lack of time, training or knowledge of the various suitable treatments.

900 deaths per year: a figure that is still unacceptable. A key issue: better information and coordination

In France, asthma is responsible for around 900 deaths every year, a significant proportion of which occur among children and adolescents.This figure is all the more worrying given that, in many cases, these deaths could be avoided through early diagnosis, improved compliance with treatment and appropriate management of exacerbations. Emergency room visits for severe exacerbations are still all too frequent, and testify to the current limits of management. In this respect, post-exacerbation follow-up is crucial.

"Today, asthma management is undergoing a true transformation, thanks in particular to the emergence of targeted biological treatments. These innovative therapies enable a more personalized approach, taking into account the inflammatory mechanisms specific to each patient. They offer new prospects, particularly for severe forms of the disease, which have long been difficult to control. Despite these advances, access to optimal care remains highly uneven across the country. Disparities concern both access to specialists, such as pulmonologists and allergists, and patients' socio-economic conditions. Even patients with few symptoms can present a risk of serious exacerbation. The objective is therefore clear: to aim for zero emergency room visits ", explains Pr Pascal Chanez, allergist pulmonologist at AP-HM and member of the CRISALIS network

Faced with these findings, one of the major challenges is to train the various healthcare professionals involved and harmonize messages.

"The coordination of players is clearly an essential lever for improvement. Patients must receive a coherent and homogeneous discourse from the various professionals involved in their care (GPs, pulmonologists, allergists, pharmacists), in order to avoid any confusion and favor their adherence to treatment. Each medical consultation should be an opportunity to reassess asthma control.The development of tools such as the shared medical record or the growing involvement of pharmacists, notably in the vaccination of asthma patients, are a step in this direction, but still need to be structured" continues Pr Arnaud Bourdin, Head of the Pneumology, Allergology and Thoracic Oncology Department at Montpellier University Hospital, and member of the CRISALIS network.

Prevent rather than cure

Experts from the F-CRIN-labeled "CRISALIS" national network remind us that asthma management must be part of a whole patient approach, integrating environmental and behavioral dimensions. Exposure to allergens and pollution, as well as lifestyle habits such as smoking, vaping and diet, play a decisive role. Physical activity is also encouraged, provided it is adapted and experienced in a positive way, as an element of quality of life and not as a constraint.

Digital tools and monitoring applications can help improve compliance, provided they are adapted to patients' uses and expectations. In this context, certain artificial intelligence solutions capable of facilitating access to scientific recommendations for healthcare professionals could also play an increasing role in the years to come.

Beyond treatments, research is increasingly focusing on prevention. In particular, current work is exploring the impact of the environment from the earliest stages of life, including during pregnancy. The aim is to better understand the interactions between genetic and environmental factors in order to limit the onset and worsening of the disease.

Major appointments

To find out more about all the latest news on asthma, an appointment for healthcare professionals with the world's leading experts, accessible online will take place on the occasion of World Day on May 5: an ERS / Respiratory channel Round Table from 5pm to 6pm. Registration: ICI (fee for non-ERS members).

Initiatives to raise awareness of respiratory health issues, aimed at the general public and supported by the Fondation du Souffle, are also deployed throughout the year, with a highlight on May 5 and throughout the month in numerous healthcare establishments.

CRISALIS (Clinical Research Initiative in Severe Asthma: a Lever for Innovation & Science), is a dynamic French network dedicated to clinical research in severe asthma, made up of 16 member centers - the CHU of Bichat (Paris) and Lyon (coordinating centers), the CHU of Besançon, Bicêtre (Paris), Bordeaux, Dijon, Grenoble, Lille, Marseille, Montpellier, Nantes, Pointe-à-Pitre (Guadeloupe), Reims, Strasbourg and Toulouse, as well as Hôpital Foch (Suresnes) - and 25 partner centers (hospitals, clinics, private lung specialists) throughout France. Bringing together French severe asthma professionals, clinicians, researchers and members of the French (Société de Pneumologie de Langue Française, SPLF) and European (European Respiratory Society,ERS) learned societies, CRISALIS has been working since 2018 to bring national and international projects to fruition, as well as better care for patients suffering from severe asthma. The network aims to foster the emergence of academic and industrial research projects to improve diagnosis and therapeutic strategies and increase the international visibility of French research in the field of severe asthma. For further information: https://www.crisalis-network.org/

Set up in 2012, F-CRIN (French Clinical Research Infrastructure Network) is a national platform dedicated to the development of French clinical research. It is led by Inserm in association with hospitals, healthcare industrialists and universities, and supported by the French National Research Agency and the Ministry of Health. F-CRIN's mission is to federate clinical research players in order to boost the international competitiveness and attractiveness of French research, develop the expertise of professionals by pooling know-how, resources and means, and thus accelerate the adoption of new practices and the development of new therapeutic solutions. Today, F-CRIN is based on a federative model structured around 28 components: 26 thematic research and clinical investigation networks, a state-of-the-art multiservice platform available to sponsors and investigators to support their trials, and a national coordination unit, the infrastructure's headquarters, based in Toulouse. With more than 2,000 professionals pooling their expertise and resources, F-CRIN is also the French interface for the European clinical research network ECRIN, promoting the participation of French teams and centers in multinational clinical trials. For further information: https://www.fcrin.org

Press contact : EVE'VOTREDIRCOM - 06 62 46 84 82 - servicepresse@votredircom.fr

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Updated on 20 April 2026